Hi Edward and relax-users, I was again thinking about the ideal processing strategy of my R1/R2 relaxation and HetNOE planes. Routinely in the past, I used the Topspin Sine-Bell functions and linear prediction for resolution enhancement in the indirect dimension. Now, I use NMRpipe with Lorentz-to-Gauss windows, but with my collected data, I hardly get the needed resolution without having severe truncation artifacts from my strong peaks wich contaminate neighbouring peaks' intensities. The latter issue is why I don't use two sets of processing parameters (one for intense and one for weak peaks), but fiddle around with overlapping peaks. I know that you advise to avoid linar prediction, but after reading http://spin.niddk.nih.gov/NMRPipe/ref/nmrpipe/lp.html I have the impression that LP could help ease the problem of truncation artifacts. I also did some literature searching, but I didn't find anything about LP making peak height measurements unreliable. I remember we discussed that during your visit, and I showed you the graphs where I compared rates calculated from spectra without LP vs. rates from spectra where the same number of points was added by LP. Maybe you remember, there was no visible bias, but rates with large errors also became larger. So what again is the reason to not use LP for relaxation series? Cheers, Martin
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