For the residual dipolar coupling (RDC) and pseudocontact shift (PCS) NMR phenomena, both effects are governed by the partial molecular alignment tensor A. For a two domain molecular system, when one domain is internally aligned with for example a paramagnetic lanthanide ion within a magnetic field, the other domain experiences a reduced alignment due to the interdomain motions.
The residual dipolar coupling is given by
where is the internuclear unit vector, d is the dipolar constant defined as
μ_{0} is the permeability of free space, γ_{i} is the gyromagnetic ratio of the nucleus i, is Planck's constant divided by 2π, 〈r〉 is the time averaged internuclear distance, the factor of is to convert the constant from radians per second to Hertz, and the factor of three is associated with the alignment tensor. In the presence of an alignment tensor reduction, and assuming that the fast vibrational and librational internal motions of the vector are statistically selfdecoupled from the rigid body motions, the RDC is simply
as the vector is considered time independent in the molecular reference frame.
The pseudocontact shift equation is simply
where A is the alignment tensor, χ is the magnetic susceptibility tensor, is the lanthanide to nuclear unit vector, and c is the PCS constant defined as
The alignment tensor reduction process is complicated by the inverse r normalisation factor, as r is not time independent in the molecular reference frame.
The statistical mechanics behind the alignment tensor reduction can be expressed as
= R^{1}(Ω_{t})⋅A⋅R(Ω_{t}) dt,

(12.37) 
where the angular brackets denote the ensemble averaging, the time integration is for a single molecule over the evolution period of the physical interaction, Ω_{t} are the SO(3) rotational angles describing the change in position of the moving rigid body, and A is the full alignment tensor. Here the alignment tensor has been created by an averaging of the partially restricted Brownian diffusion process of the nonmoving component, again both over the ensemble and time, as
A = R^{1}(Ω_{t})⋅F⋅R(Ω_{t}) dt,

(12.38) 
where F is the molecular frame. It is assumed that the alignment process of the nonmoving domain and the motions of the moving domain are decoupled.
Using the ergodic hypothesis, the averaging process which generates the reduced alignment tensor can be simplified as
The index notation for a tensor rotation is
T_{ij}' = R_{ki}R_{lj}T_{kl}.  (12.40) 
Therefore the reduced alignment tensor in index notation is
= A_{kl},  (12.41)  
= Daeg^{(2)}_{kilj}A_{kl},  (12.42) 
where Daeg^{(2)} is a rank4, 3D orientational tensor which will be called the frame order tensor.
Expanding the sum,
= Daeg_{xixj}A_{xx} + Daeg_{xiyj}A_{xy} + Daeg_{xizj}A_{xz}  
+Daeg_{yixj}A_{yx} + Daeg_{yiyj}A_{yy} + Daeg_{yizj}A_{yz}  
+Daeg_{zixj}A_{zx} + Daeg_{ziyj}A_{zy} + Daeg_{zizj}A_{zz}.  (12.43) 
As
equation 12.43 becomes
= Daeg_{xixj}  Daeg_{zizj}A_{xx} + Daeg_{yiyj}  Daeg_{zizj}A_{yy}  
+ Daeg_{xiyj} + Daeg_{yixj}A_{xy} + Daeg_{xizj} + Daeg_{zixj}A_{xz} + Daeg_{yizj} + Daeg_{ziyj}A_{yz}.  (12.45) 
A single element of the reduced tensor is simply a linear combination of all elements of the original tensor multiplied by constants consisting of different combinations of frame order matrix components.
Converting from the rank2, 3D, symmetric and traceless space of alignment tensors to the rank1, 5D space, a nonlinear frame order superoperator can be written as
In matrix notation, this is
Let
A_{0}, A_{1}, A_{2}, A_{3}, A_{4} = A_{xx}, A_{yy}, A_{xy}, A_{xz}, A_{yz},  (12.48) 
and assuming the rank2, 9D Kronecker product form of Daeg^{(2)}_{ij} using numerical indices where {i, j} = 0, 1,..., 8, then
= ⋅.  (12.49) 
For the alignment tensor, the 81 elements of the frame order matrix have recombined into 25 unique scaling factors.
The alignment tensor is related to the orientational probability tensor by
A = P  I.  (12.50) 
The P probability tensor is the average orientation position of the molecule, hence is the average molecular frame . As this frame is simply the rotation matrix relative to the laboratory frame, then
Therefore the alignment tensor can then be written as the anisotropic part of the first degree frame order matrix
A = Daeg^{(1)}  I.  (12.52) 
The relax user manual (PDF), created 20190308.